Marginal microleakage of newly synthesized nanostructured materials based on calcium aluminate after application in interradicular perforations

Introduction. Marginal seal or adequate marginal adaptation of material along the cavity walls should be able to prevent leakage tissue fluid and consequently bacterial microleakage, terefore, it is considered as significant factor for long term success endodontic treatment. The aim this work was test microleakage newly synthesized nanostructured biomaterials based on calcium aluminate, silicate MTA with a dye penetration after application interradicular perforations extracted teeth. Material method. study included 48 human maxillary mandibular molars. Newly materials were tested: silicate. Commercial cement (MTA Angelus, Londrina, Brazil) used control material. examined six months in experimentally prepared Penetration depth measurement analyzed binocular magnifier (Leica DM 500, Leica Byosistems). Results are expressed millimeters statistically processed by applying analysis variance repeated measurements Sidak test. Results. lowest average (mm) (1.40 ? 0.63 mm), highest Ca aluminates (2.10 while silicates an color 1.73 0, 67mm recorded. By testing intergroup differences between groups, difference aluminate obtained using Sidak?s (t = -0.693; p 0.036). No recorded silicate, nor there Conclusion. best sealing, aluminate-based significantly higher compared MTA.